Therapeutic Efficacy Observation on Acupuncture for Primary Xerostomia

针刺治疗原发性口干燥症疗效观察(英文)

Objective： To observe the clinical effect of acupuncture therapy for primary xerostomia. Methods： A total of 46 cases were randomly allocated into an acupuncture group and a medication group by the random alphabet table. Cases in the acupuncture group were treated with acupuncture aiming to nourish yin and tonify the kidney, whereas cases in the medication group were treated with oral administration of Zhi Bai Di Huang Wan （Anemarrhena, Phellodendron and Rehmannia Pill）. Then the static total saliva flow rate and cube sugar dissolving scores in the two groups before and after treatments were compared and analyzed. Results： The total effective rate in the acupuncture group was 87.0%, versus 60.9% in the medication group, showing a statistical significance （P〈0.05）. After treatment, the static total saliva flow rates and cube sugar test scores were significantly improved in both groups （P〈0.05 or P〈0.01）, there were statistical differences regarding both the static total saliva flow rates and cube sugar test scores between the two groups （P〈0.01）. Conclusion： Acupuncture therapy aiming to nourish yin and tonify the kidney could achieve better results than oral Zhi Bai Di Huang Wan （Anemarrhena, Phellodendron and Rehmannia Pill） and cause no adverse reactions.

目的:观察针刺治疗原发性口干燥症的临床疗效。方法:将46例患者按随机字母表随机分入针刺组和药物组。针刺组予以滋阴补肾针刺治疗,药物组口服知柏地黄丸治疗。对两组患者治疗前后静态唾液总流率及方糖试验计分变化进行比较分析。结果:针刺组总有效率87.0%,药物组总有效率60.9%,两组总有效率比较,差异有统计学意义(P<0.05)。治疗后,两组静态唾液总流率测定、方糖试验计分均明显改善,同组治疗前后比较差异均有统计学意义(P<0.05或P<0.01);治疗后,针刺组静态唾液总流率、方糖试验计分与药物组比较差异均有统计学意义(P<0.01)。结论:滋阴补肾针刺疗法治疗原发性口干燥症疗效优于口服知柏地黄丸,且无不良反应。