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胃癌术后输注脂肪乳对IL-12及细胞免疫功能的影响 被引量:1

胃癌术后输注脂肪乳对 IL-12及细胞免疫功能的影响
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摘要 脂肪乳剂对胃癌术后患者免疫功能的影响目前还存在着争论.本文旨在通过检测胃癌根治术后患者的 IL-12及 T 细胞亚群,了解输注脂肪乳剂对机体免疫功能的影响.1 材料和方法1.1 材料选择术前经病理证实的胃癌住院患者34例,随机分成2组:实验组(TPN)组20例,对照组14例.入选条件:①有典型的临床症状;②肝功能正常,无代谢性疾病,术前未应用免疫治疗或放、化疗;③术前无明显重要脏器转移.两组患者的临床资料、肿瘤部位、病理类型、分期、手术方式等均无显著差异,手术探查证实均无邻近及重要脏器转移.另取16份正常人血清做正常人群对照.1.2 方法实验组术后 d1起,每天静脉输注200 g/L 脂肪乳剂250mL,70 g/L 乐凡命1000mL,100 g/L 葡萄糖液2000mL,连用8 d~9 d;对照组术后给予常规补液,无脂肪乳剂及氮供给.
出处 《世界华人消化杂志》 CAS 2000年第6期712-713,共2页 World Chinese Journal of Digestology
关键词 胃肿瘤 脂肪乳剂 细胞免疫 EL-12 stomach neoplasms interleukin-12 subgroup of T lymphocyte
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