摘要
目的:优选血散薯总生物碱的提取工艺。方法:以总生物碱得率为指标,采用单因素和正交试验法考察乙醇体积分数、料液比、提取时间、pH对血散薯总生物碱得率的影响。结果:血散薯中总生物碱的最佳提取工艺为16倍量70%乙醇提取2.0 h,pH 2.0。结论:该优选工艺能较好的提取血散薯中的生物碱。
Objective:To optimize extraction technology of total alkaloids in Stephania dielsiana.Method: With yield of total alkaloids as index,effect of the concentration of ethanol,solid-liquid ratio,extraction time and pH on yield of total alkaloids was investigated by orthogonal test and single factor test.Result: The best extraction conditions were as follows:extracted 2 h with 16 times the amount of 70% ethanol,pH 2.0.Conclusion: This optimized technology was suitable for extraction of total alkaloids in S.dielsiana.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第14期36-38,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
973计划前期研究专项(2007CB516805)
广西科技厅应用基础研究(桂科基0731050)
药用资源化学与药物分子工程教育部重点实验室主任基金(CMEMR2011-19)
广西自然科学基金创新团队项目(2010GXNSFF013001)
关键词
血散薯
生物碱
提取
离子交换树脂
Stephania dielsiana
alkaloids
extraction
ion exchange resin