素馨花中的酚性成分

Phenols from Buds of Jasminum officinale

目的:研究木樨科植物素馨干燥花蕾的抗乙型肝炎病毒(HBV)活性化学成分。方法:通过硅胶柱色谱、大孔树脂柱色谱并结合重结晶等方法进行分离纯化,根据化合物的理化性质和波谱数据鉴定化学结构。结果:从素馨干燥花蕾70%乙醇提取物的抗HBV活性部位中,分离得到5个酚性化合物,分别鉴定为7-羟基-6甲氧基香豆素(1)、没食子酸乙酯(2)、对苯二酚(3)、2-(4-羟基-苄基)-苹果酸(4)、红景天苷(5)。结论:化合物1～5均为首次从本植物中分离得到。

Objective：The study on the buds of Jasminum officinale was carried out to look for anti-hepatitis B rirus（HBV） constituents.Method： The isolation and purification were performed by chromatography on silica gel column and macroporous resin column.The structures were elucidated on the basis of physicochemical properties and spectral analysis.Result： Five phenols were identified as scopoletin（1）,ethylgallate（2）,1,4-benzenediol（3）,2-（4-hydroxybenzyl）-malic acid（4）,salidroside（5）.Conclusion： Compounds 1~5 were isolated from Jasminum officinale for the first time.