三子平喘颗粒治疗儿童喘息性呼吸道感染

Effects of Sanzi Pingchuan Granule on Treating Children with Asthmatic Respiratory Tract Infection

目的:评价三子平喘颗粒用于儿童喘息性呼吸道感染的临床疗效。方法:将50例呼吸道感染伴有喘息的患儿随机分为对照组和治疗组。对照组采用常规西医治疗(抗生素、抗病毒、雾化吸入、以及糖皮质激素类药物及必要的支持对症治疗),治疗组在对照组的基础上给予三子平喘颗粒口服,疗程7 d,治疗后评价临床疗效。结果:两组治疗前后比较均疗效显著,治疗组在咳嗽,咳痰,肺部体征各指标疗效、症状综合评分改善程度以及总有效率与对照组比较差异无统计学意义,但在治疗5 d,7 d时的气促喘息的改善上治疗组优于对照组[(评分分别为(0.28±0.84)vs(0.92±0.57)分,(0.08±0.28)vs(0.32±0.56)分],(P<0.05)。结论:在西医常规治疗基础上加用三子平喘颗粒治疗儿童喘息性呼吸道感染,可有效缓解气促喘息症状,治疗效果较单纯使用西药更佳,值得临床推广应用。

Objective：To evaluate the effect of Sanzi Pingchuan granule on treating children with asthmatic respiratory tract infection.Method： Fifty cases of asthmatic respiratory tract infection in children were randomly divided into control group and treatment group（25 cases each）.Control group was given conventional western treatment（antibiotics,antivirotic,aerosol inhalation,corticosteroids and necessary supportive therapy）.Treatment group was given Sanzi Pingchuan granule on the basis of western treatment.Both groups were treated for seven days as a course,then to evaluate the clinical efficacy.Result： Both groups showed significant effect after treatment compared to before,respectively.Although there were no significant differences in the degree of improvement in cough,sputum,pulmonary wheezing sound and coarse rales,composite score and the total effective rate between control group and treatment group,treatment group significantly alleviated wheezing and panting symptom on fifth and seventh day compared with control group（0.28±0.84 vs 0.92±0.57,0.08±0.28 vs 0.32±0.56,respectively,P0.05）.Conclusion： Sanzi Pingchuan granule combined with western treatment for treating children with asthmatic respiratory tract infection appears to be significantly effective on alleviating wheezing and panting compared with western treatment alone.The therapeutic approach might be widely applied.