蛞蝓提取物对人肺癌细胞A549的抑制作用

The Inhibitory Effects of Land Slug Extractive on A549 Cell

目的:了解蛞蝓提取物对人肺癌细胞A549的抑制作用及对细胞形态学的影响。方法:用MTT法测定蛞蝓提取物对A54 9细胞的增殖抑制率,并观察其形态学变化。结果:蛞蝓提取物能抑制A549细胞的增殖,抑制率为11.1%～66.51%;镜下可见肺癌细胞呈变小、变少、破碎裂解等变化。结论:蛞蝓提取物对人肺癌A549细胞有显著的抑制作用。

Objective：To find out the inhibitory effects of land slug extractive on A549 cell and the effect on cell morphology.Methods：MTT method was used to detect inhibition ratio to A549 cell and the morphological changes were observed by electron microscopy.Results：Land slug extractive could inhibit the proliferation of A549 cell,the suppression ratio was 11.1%~66.51%.It showed lung cancer cell diminishing,tailing off and schizolysis.Conclusion：Land slug extractive possesses the obvious effects on A549 cell.