摘要
在Fe3O4纳米粒子表面聚合包覆温敏性聚N-异丙基丙烯酰胺(PNIPAM)及其与聚苯乙烯(PS)、聚α-甲基丙烯酸(PMAA)的共聚物,制备表面不同亲水/疏水性质的双重磁响应温敏复合微球。利用透射电镜(TEM)、红外光谱(FT-IR)及Zeta粒度仪(DLS)等对复合微球进行了表征。结果表明,复合微球呈现核壳结构,粒径约为150nm^300nm;在复合微球温敏聚合物中引入亲水/疏水链段可以有效调节其最低临界溶解温度(LSCT),随着温敏聚合物亲水性的提高,微球LSCT向高温移动,且该微球具有良好的双重磁响应特性(磁靶向响应性和磁热响应性)。
Fe3O4 nanoparticles were encapsulated with various thermo-sensitive polymer including poly (N- isopropylacrylamide), poly(N-isopropylacrylamide-co-styrene) and poly(N-isopropylacrylamide-co-methacrylic acid) to form thermo-sensitive composite-microspheres with dual-magnetic responses. The composite-microspheres were characterized by transmission electron microscope (TEM), Fourier transform infrared spectra(FT-IR) and dynamic light scattering (DLS). The results indicate that the composite-microspheres are characterized with a magnetic Fe3O4 core, a polymer shell, and an average diameter of about 150 nm-300 nm. The lower critical solution temperature (LSCT) of composite-microspheres can be controlled by introduction of different polymer-units (hydrophilic or hydrophobic) onto thermo-sensitive poly (N-isopropylacrylamide) chains, and the LSCT moves to higher temperatures as the contents of hydrophilic polymer-units increase. Besides, the above composite-microspheres also possess dual-magnetic responses (including magnetic delivery and magnetic-thermal effects).
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2012年第7期120-123,共4页
Polymer Materials Science & Engineering
基金
福建省自然科学基金资助项目(2009J05131)
莆田市科技计划项目(2009G25)
关键词
N-异丙基丙烯酰胺
双重磁响应
温敏
复合微球
poly(N-isopropylacrylamide)
dual-magnetic responses
thermo-sensitive
composite-rnicrospheres