缺血性心肌病

Ischemic cardiomyopthy

文章从缺血性心肌病(ICM)的定义、病因及发病机制、临床表现及辅助检查和治疗及其进展等方面描述了ICM是心肌缺血导致心脏扩大,心功能下降但不能用冠状动脉病变程度解释。临床主要表现为心力衰竭的症状和体征,心室节段性室壁运动障碍,射血分数下降;最后,着重介绍了ICM治疗及其进展,在药物治疗的基础上,选择血管重建、心脏再同步化治疗、干细胞治疗、人工辅助循环和心脏移植。

This article reviewed that ischemic cardiomyopathy （[CM） was myocardial ischemia resulting in heart enlarge ment and reduced heart functions which can not explained by the degree of coronary artery stenosis according to the defini tion, causes, pathogenesis, clinical manifestation, assistant examinations, treatments and progressionadvanced therapy of ICM. The manifestations of ICM were mainly the symptoms and physical signs of heart failure, ventricular segmental wall dyskinesis and decreased ejection fraction. Finally, the treatment and development of ICM was highlighted involving selection of vascular remodeling, cardiac resynchronization therapy, stem cell therapy, assisted circulation and heart transplantation based on drug treatment.