肺癌中循环肿瘤细胞的检测

Detection technique of circulating tumour cells in lung cancer

循环肿瘤细胞为肿瘤复发转移的重要原因，检测循环肿瘤细胞能早期发现肿瘤的转移及复发，同时也将有助于判断疾病预后、指导治疗。循环肿瘤细胞检测通常包含有筛选和分离技术如免疫磁性分选技术和逆转录聚合酶链反应等。随着检测技术的发展出现了将筛选和分析技术合为一体的循环肿瘤细胞检测芯片。

Circulating tumor cells （CTCs） are essential for establishing recurrence and metastasis in malignant tumors. Detecting CTCs can help for early detection of the cancer metastases and recurrences, and also can help for evaluating prognostic and guiding treatment. CTCs detection technique mainly include screen- ing and separation technology which contains immune magnetic separation technology and reverse transcriptase- polymerase chain reaction and so on. With the development of technique, there is a new technique named etcchip contains both screening and separation functions.