摘要
基因的表达对胃癌的药物治疗有着十分重要的影响，有的基因与药物的疗效相关，有的基因与药物的不良反应相关，而有的基因则与肿瘤对药物的敏感性相关。胃癌化疗相关基因的研究对提高患者化疗疗效有着重要的指导作用。近年来对胃癌化疗相关基因的研究取得了较大进展，特别是在铂类、嘧啶类、紫杉醇类以及靶向药物相关基因的研究。
The expression of genes have an important effect to gastric cancer chemotherapy. Some genes are related the therapeutic efficacy of drugs, some genes are related the untoward effects of drug, and some genes are related the sensitivity of the tumor to drug. Chemotherapy related genes may play an important guiding role to improve the curative effect of chemotherapy patients. In recent years, the gastric cancer chemo- therapy related genes have made great progress, especially in platinum, fluorouracil, paclitaxel and targeted medicine related genes.
出处
《国际肿瘤学杂志》
CAS
2012年第7期533-537,共5页
Journal of International Oncology
关键词
胃肿瘤
药物疗法
基因表达
Stomach neoplasms
Drug therapy
Gene expression
