NAC对急性加重期慢性阻塞性肺疾病患者影响的临床观察

目的观察N-乙酰半胱氨酸（NAC）在治疗过程中对急性加重期慢性阻塞性肺疾病（AECOPD）患者的临床影响。方法选择AECOPD患者70例，随机均分为对照组和观察组，对照组给予常规药物治疗，观察组在上述治疗基础上口服NAc治疗，治疗1周后比较两组患者肺功能指标、血液学指标及临床效果。结果两组患者治疗1周后肺功能指标、血液学指标、临床效果比较，差异均有统计学意义（P〈0．05），观察组均优于对照组。结论在AECOPD的治疗过程中，应口服NAc治疗，可提高临床疗效。

Objective To observe the clinical effect of NAC in patients with acute exacerbation of chronic obstructive pulmonary disease. Method 70 patients with acute exacerbation of chronic obstructive pulmonary disease were enrolled, they were divided into the control group and the observation group, the pulmonary function indexex, hematological indexes and clinical effect after 1 week＇ s treatment were compared. Result There was a statistical significant （ P〈0.05 ） in the pulmonary function index, hematological indexes and clinical effect after l week＇ s treatment, the observation group was better than the control group. Conclusion In the course of treatment ofAECOPD, the oral NAC treatment might improve the clinical outcomes.