潮气呼吸肺功能动态监测在毛细支气管炎治疗中的作用

Efffect of lung function test via tidal breathing in the treatment for bronchiolitis

目的分析潮气呼吸肺功能动态监测在毛细支气管炎治疗中的作用。方法对60例毛细支气管炎患儿分别于感染急性期、治疗后1周及恢复期1个月行潮气呼吸肺功能测定,主要测定参数为达峰时间比(TPTEF/TE)、达峰容积比(VPTEF/VE)、峰流速(PEF),比较各期肺功能指标及潮气流速容量环(TBFV环)变化。结果毛细支气管炎患儿感染急性期小气道指标TPTEF/TE、VPTEF/VE明显低于治疗后1周及恢复期1个月,大气道指标PEF高于治疗后1周及恢复期1个月;各期比较,急性期与治疗后1个月比较有显著性差异(P均<0.05),TBFV环渐趋饱满。结论毛细支气管炎患儿急性期为克服以小气道为主的气道阻塞,存在用力呼气,经治疗1周后各项指标明显好转,但仍低于恢复期,表明毛细支气管炎患儿急性期过后仍应坚持非特异性抗炎治疗;TPTEF/TE、VPTEF/VE等潮气呼吸肺功能测定可较好反映病情,评价喘息患儿气道阻塞变化。

Objective It is to analyze the effect of lung function test via tidal breathing in the treatment for bronchiolitis. Methods 60 children with bronchiolitis were measured with tidal flow volume curve function test in acute phase, then the test was repeated after 1 week and 1 month later. The main parameters were： time to peak ratio（TPTEF/TE） ,peak volume ratio （VPTEF/VE） ,peak expiratory flow （PEF） ,comparing the changes of lung function and tidal breathing flow volume. Results In acute period, the index of TPTEF/TE, VPTEF/VE were significantly lower but the index of PEF were higher than that in 1 week and lmonth later. There were significant differences in the indexes between acute phase and 1 month, and TBFV loop was becoming full. Conclusion The children with bronchiolitis have alteration of airway obstruction, mainly in small airway, the indicators are improved markedly in 1 week after treatment, but still lower than the recovery of 1 month. It shows that after the acute phase of bronchiolitis, the patients should adhere to non-specific anti-inflammatory treatment. TPTEF/TE, VPTEF/ VE and other tidal breathing lung functionmay may have a better response to the disease and evaluation for the changes in air- way obstruction in children with wheezing.