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培美曲塞联合奥沙利铂治疗晚期非小细胞肺癌疗效观察 被引量:1

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摘要 目的评价培美曲塞联合奥沙利铂治疗晚期非小细胞肺癌的疗效及安全性。方法选择经病理学确诊,接受2个周期以上的化疗及失败的复发晚期非小细胞肺癌患者24例,给予培美曲塞500 mg/m2第1天+奥沙利铂120 mg/m2第1天静滴,每3周重复治疗1次,至少应用2个周期评价疗效及不良反应。结果 24例患者中,完全缓解2例,部分缓解4例,稳定10例,进展8例,有效率25%,疾病控制率67%。不良反应主要为轻中度的胃肠道反应和骨髓抑制。结论培美曲塞联合奥沙利铂治疗晚期复发性非小细胞肺癌疗效确切,不良反应轻,安全性好。
出处 《现代中西医结合杂志》 CAS 2012年第23期2568-2569,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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