新生儿坏死性小肠结肠炎66例临床危险因素分析

目的研究新生儿坏死性小肠结肠炎(NEC)相关危险因素和临床特征的变化,为降低其死亡率提供方法。方法将66例NEC患儿分为两组,对其临床资料、出生情况、预后进行回顾性分析。结果与前5年相比,近5年NEC的致病因素中,早产(胎龄<33周)、低出生体重(<1500g)和胎膜早破(时间>24h)更为突出。结论早产和感染仍是NEC重要的致病因素,早产儿胎膜早破是发生NEC的高危因素。减少早产和积极控制感染,是目前预防NEC发生的主要策略。

Objective To investigate the changers of the risk factors and clinical features of neonatal necrotizing enterocolitis （NEC） and find some strategies to improve the survival rate of NEC. Methods Then on66patients of NEC were divided into two groups, of which the Clinical data, is born, the prognosis were retrospectively analyzed, Results Compared with the previous 5 years,the preterrn （gestatioaal age〈33W）,low birth weight （birth weight〈1500g） and premature rupture of membranes （over 24 hours） become more risk factors of NEC in recent 5 years. Conclusion Premature and infection are still two more risk factors of NEC,Preterm Premature Rupture of Membranes is a high-risk factor ef NEC. Diminishing premature delivery and actively controlling infection may be the effective strategies for the prevention of NEC.