左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的疗效比较

目的对比左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的疗效。方法选取2011年1月～2012年1月收治的消化性溃疡患者共160例,随机分为实验组和对照组,其中实验组采用左氧氟沙星三联疗法治疗,而对照组采用阿莫西林三联疗法治疗。结果实验组患者的总有效率优于对照组,差异具有统计学意义(92.50%vs86.25%,P<0.05);两组患者不良反应发生率比较,差异无统计学意义(15.00%vs12.50%,P>0.05)。结论左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的临床疗效相当,两者不良反应也较低,若考虑到经济费用因素,则左氧氟沙星三联疗法较易于推广。

Objective Compare the clinic effect of levofloxacin triple therapy and amoxicillin triple therapy on peptic ulcer. Methods 160 patients of peptic ulcer from Jan 2011 to Jan 2012 divided into 2 groups. The experiment group used levofloxacin triple therapy while the control group used amoxicillin triple therapy. Results The diverse of clinic effect of 2 group have significance （92.50% vs 86.25%, P〈0.05）. The diverse of untoward reaction of 2 group have no significance （15.00% vs 12.50%, P〉0.05）. Conclusion The clinic effect c,f levofloxacin triple therapy and amoxicillin triple therapy on peptic ulcer are similar. The untoward reaction of two therapy is low. But the levofloxacin triple therapy is easily widely used for lower fee.