D-二聚体、脂蛋白(a)、纤维蛋白原和冠心病关系研究进展

Research Progress on the Relationship of Coronary Heart Disease and D-dimer,Lipoprotein(a),Fibrinogen

冠心病(CHD)与D-二聚体、脂蛋白(a)、纤维蛋白原(FG)有着密切的关联,CHD患者中D-二聚体、脂蛋白(a)、FG较高,但它们之间相互作用的机制仍不明确。近年来的研究显示,D-二聚体、脂蛋白(a)和FG可能参与CHD的发病过程,因此通过测定D-二聚体、脂蛋白(a)和FG在不同危险程度的CHD患者中的含量,评估它们对于CHD的发生、发展具有重要意义。

Coronary heart disease（CHD）is closely associated with D-dimer,lipoprotein（a）and fibrinogen（FG）,CHD patients have higher levels of D-dimer,lipoprotein（a）,fibrinogen while the mechanism of the interaction between them remains unclear.In recent years,studies have shown that D-dimer,lipoprotein（a）and fibrinogen may be involved in the pathogenesis of coronary heart disease,so by measuring D-dimer,lipoprotein（a）and fibrinogen level in patients with coronary heart disease is of great significance for assessing the genesis and development of CHD.