经济型PET／CT对肺部病变诊断的临床应用

The Clinical Use of Diagnosing the Lung Lesion with E-PET/CT

目的探讨E-PET／CT显像对肺部病变诊断的临床价值。方法选择接受 ^18F-FDCE-PET／CT检查的50例肺部病变患者，其中，男33例，女17例。对良、恶性病变的T／NT比值及E-PET／CT的诊断结果与病理或密切观察随访1年以上得到最终诊断进行比较。结果50例患者E．PET／CT诊断为恶性病变35例，良性病变15例。良、恶性病变的T／NT比值分别为2．23±4．41，7．11±0．88，二者比较，差异有显著性（P〈0．05）；E-PET／CT与病理和观察随访最终诊断结果对照分析，发现E-PET/CT对肺部病变诊断的灵敏度为91．1％，特异性75％，准确性86％，阳性预测值88．7％及阴性预测值80％．结论E-PET／CT对肺部病变的诊断有重要的临床价殖，

Objective To investigate the clinical value of diagnosing the pulmonary lesion with E-PET/CT. Methods Fifty patients with pulmonary lesion were studied with ^18F-FDG E-PET/CT. The differences of the target/non- target（T/NT） ratio were compared between tile malignant and benign pulmonary lesion. The diagnostic results by E- PET/CT were compared with pathological analysis or followed up more than 1 year. Results Thirty five patients with malignant lesion and 15 patients with benign lesion were diagnosed with E-PET/CT. The T/NT ratios between the benign （2.23 ± 4.41 ） and malignant（7.11 ± 0.88） puhnonary lesion that were significantly different（ P 〈 0.05） ;The sensitiv- ity, specificity, accuracy, positive predictive value and negative predictive value of diagnosing the pulmonary lesions by E- PET/CT were 91.1% ,75% ,86% ,88.7% and 80% ,respectively. Conclusion It is vet,y serviceable to diagnose the pulmonary lesions with E-PET/CT.