利多卡因和维生素B12鼓室内灌注治疗耳鸣的疗效分析

The Analysis of the Efficiency of Transtympanic Vitamin B12 and Lidocaine Treatment for Subjective Tinnitus

目的探讨维生素B12和利多卡因混合注射液鼓膜穿刺法鼓室内灌注治疗耳鸣的疗效。方法68例行鼓室灌注2％利多卡因注射液0．2ml和维生素B12注射液1ml的混合液0．5ml；58例行鼓室灌注2％利多卡因注射液5ml。应用耳鸣残疾评估量表记分法来评价腺样体手术的治疗效果。结果治疗组68例耳鸣患者治疗后6个月评分为（6．42毒6．43）分，对照组58倒耳鸣患者治疗后6个月评分为（12．66±11．14）分（P〈0.05）。结论鼓室灌注2％利多卡因注射液和维生素B12注射液混合液治疗耳鸣方法简单、安全，效果好，值得临床推广。

Objective To determine whether transtympanic Vitamin B12 and Lidocaine administration may be an effective treat- ment for subjective tinnitus patients or not. Methods In the Study Group,68 cases were reiceived transtympanic Vitamin B12 and Lidocaine administration. In the Control Group,58 cases were only reiceived transtympanie Lidocaine treatment. Results The postoperative THI scores of 68 cases in the study group ranged from 18 to 76,the mean score was 6.42 ± 6.43. The postoperative THI scores of 58 cases in control group ranged from 18 to 76,the mean score was 12.66 ± 11. 14 （ P 〈 0.05 ）. Conclusion Transtympanic Vitamin BI2 and Lidoeaine Treat- ment for Subjective Tinnitus is safety and simple method based on the pathogenesis. It is obviously better methods than other. The long term therapeutic effect remains to be further studied.