慢性脑供血不足(CCCI)的脑血流灌注成像研究进展

Advancement of cerebral blood perfusion imaging in chronic cerebral circulation insufficiency

脑血流灌注不足是CCCI的主要病理生理机制。目前用于评价脑血流量的方法有CT灌注成像(CTPI)、磁共振灌注加权成像(PWI)、正电子发射性体层显像(PET)、单光子发射性体层扫描(SPECT)、氙气CT-灌注成像(Xe-CT)等。利用CT、MRI等影像学技术可显示CCCI低灌注损伤的范围和程度,早期发现脑缺血,有效避免脑梗死、血管性痴呆的发生。

Hypoperfusion is the main pathophysiology of CCCI. The techniques used to evaluate CBF include CTPI, PWI, PET, SPECT and Xe-CT. CT and MRI perfusion imaging could show the extent and degree of hypoperfusion injury and effectively avoid the developement of cerebral infarct or vascular dementia.