桥本氏甲状腺炎合并甲状腺乳头状癌超声分析

Analyses of 35 cases of papillary thyroid carcinoma under the background of Hashimoto's thyroiditis

目的:探讨桥本甲状腺炎(HT)合并的甲状腺乳头状癌(PTC)超声表现特征。方法:回顾性分析35例HT伴PTC(HT组)和57例PTC(非HT组)共92例单发癌结节患者超声图像特征,采用SPSS 16.0软件统计分析超声图像特征的差异。结果:HT组的癌结节内粗钙化比例为45.71%,明显高于非HT组的17.54%〔χ2=8.488,P=0.004,OR=3.958(95%CI:1.526-10.264)〕。非HT组中癌结节多表现为低回声伴微小钙化。非HT组的癌结节内微钙化的比例为63.16%,明显高于HT组的34.29%〔χ2=7.244,P=0.007,OR=1.784(95%CI:1.177-2.703)〕;且非HT组的癌结节低回声的比例为86.96%,明显高于HT组的54.28%〔χ2=11.286,P=0.001,OR=3.257(95%CI:1.559-6.806)〕。两组癌结节在大小、形态、边界及CDFI特征方面差异无统计学意义(P>0.05)。结论:分析HT合并癌结节的超声表现,有助于提高HT背景下的甲状腺癌检出率。

Objective= To discuss the ultrasonographic features of papillary thyroid carcinoma （PTC） under the back- ground of Hashimoto＇s thyroiditis （HT）. Methods.. The ultrasonographic features of single cancer node in a cohort of 92 ca- ses. which consisted of 35 cases of HT with PTC （HT group） and 57 cases of PTC （non-HT group）, were retrospectively viewed and the difference of these ultrasonographic features in two groups were analyzed by means of SPSS 16.0 statistical software in this work. Results：In the HT group, the proportion of heavy calcification in cancer node was 45. 71%, which was obviously higher than 17.54% in non-H＇r group [Xe=8.488, P =0.004. （）R=3.958 （95%CI： 1. 526-10. 264）3. In non-HT group, cancer node exhibited low echo with micro-calcification. In non-HT group, the proportion of micro-calcifi- cation in cancer node was 63.16%, which was obviously higher than a4.29% in HT group [X2 =7. 244, P =0. 007, （）R= 1. 784 （95%CI：1.177-2. 703）3. Also, the proportion of low echo from cancer node in non-HTgroup was 86.96%, which was markedly higher than 54. 28% in HT group [X2=11. 286, P =0. 001, OR=3. 257 （95% CI： 1. 559-6. 806）2. Howev- er, the attributes of cancer node in terms of size, shape, boundary, and CDFI had no statistic differences in two groups （ P 〉0.05）. Conclusion： Analyses of the ultrasonographic manifestations of HT concomitant with cancer node is helpful for improving the diagnostic rate of thyroid cancer under the HT background.