孕妇网织红细胞参数分析

The analyse of reticulocyte parameters in pregnant women

目的分析孕妇网织红细胞百分比(RET%)、未成熟网织红细胞指数(IRF)、平均网织红细胞分布体积(MRV)、球形红细胞平均体积(MSCV)、高荧光强度网织红细胞百分比(HLR%)五项参数的变化。方法采用Beckman Coulter LH750血细胞分析仪测定618例孕妇组、100例健康非孕对照组的网织红细胞参数及变化,对数据进行统计学分析。结果贫血孕妇组与正常孕妇组及正常非孕组比较,5项网织红细胞参数差异有统计学意义(P<0.05);正常孕妇组与正常非孕组比较的RET%、IRF、HLR%差异有统计学意义(P<0.05),而MRV、MSCV差异无统计学意义(P>0.05)。结论常规测定孕妇网织红细胞参数有助于了解骨髓的造血功能和机体对贫血的反应情况,对疾病的诊断、疗效观察非常有意义。

Objective To investigate the change of 5 reticulocyte parameters： reticulocyte percent （RET%）, imma- ture reiculocyte fraction （IRF）, average microsphercyte volume （MRV）, average granulofilocyte volume （MSCV）, percent- age of high light scatter reticulocyte （HLR%） in pregnant women. Methods Retieulocyte parameters in blood samples from 618 patients with pregnant women and 100 healthy non pregnant women by Beckman Coulter LH750 automatic biood cytoanalyze. Results The 5 reticulocyte parametece of pregnant women with anaemia, normal pregnant women and healthy non pregnant bah significant differece （P 〈 0. 05）, The levels of RET%, IRF, HLR% in normal pregnant women and healthy non pregnant bah significant differece （P 〈 0. 05 ）, but it had no significance in MRV, MSCV （P 〉 0. 05） . Conclusion reticulocyte pa- rameters help to understand the hematopoietic function of bone marrow and condition of body rection to anemia and a powerful tool to diagnose illness and observe curative effect.