摘要
探索不同乳化剂sp60、sp80、tw60、tw80及其复合乳化剂对坎利酮羟基化的影响。结果表明乳化剂对坎利酮有增溶作用,且tw80、复合乳化剂tw80-sp60对坎利酮微生物转化有促进作用。其中单组分乳化剂tw80的最佳质量分数为0.18%,转化率为90.32%;复合乳化剂tw80-sp60,最佳质量分数为0.09%,转化率为92.22%。
The effects of different surfactants, sp60, sp80, tw60, twS0 and their multiple surfactants, on canrenone hydroxylation are studied in this paper. The results show that the surfactants have positive effects on the substrate dissolution, and mono-surfactant twS0 and multiple surfactants tw80-sp60 have positive effects on canrenone microbial transformation. A higher conversion rate can be reached when using mono-surfactant tw80 with the mass fraction of 0.18 %, the yield is 90.32 %. As for multiple surfactants tw80-sp60, the most appropriate surfactant dosage is 0.09 %, the yield is 92.22 %.
出处
《上海应用技术学院学报（自然科学版）》
2012年第2期134-136,140,共4页
Journal of Shanghai Institute of Technology: Natural Science
关键词
乳化剂
坎利酮
微生物转化
羟基化
emulsifiers
canrenone
microbial transformation
hydroxylation
