摘要
目的:建立GC法测定感冒清热颗粒中胡薄荷酮的含量。方法:色谱柱为FFAP毛细管色谱柱(30 m×0.53 mm×1.0μm),柱温230℃,FID为检测器,选用乙酸乙酯作提取溶剂。结果:胡薄荷酮进样量在0.17～2.73μg范围内与峰面积线性关系良好(r=0.9999),平均加样回收率(n=6)为97.8%,RSD为1.0%。结论:该方法简便、可靠、准确,可用于该制剂的质量控制。
Objective： To establish the determination method of pulegone in Ganmao Qingre granules by GC. Methods：The samples were separated on a column of FFAP（30 m ×0. 53 mm × 1.0μm） ,column temperature was 230 ℃, the FID was used and the ethyl acetate was selected as the extraction agent. Results： The calibration curves showed good linearity in the range of 0. 17 -2. 73 μg（ r =0. 9999）. The average recovery（ n = 6）was 97.8% with RSD of 1.0%. Conclusion： This method is simple, reliable, accurate and can be used for the quality control of the drug.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2012年第7期1283-1284,1291,共3页
Chinese Journal of Pharmaceutical Analysis
关键词
中成药
中药复方制剂
感冒清热颗粒
荆芥穗
胡薄荷酮
气相色谱法
质量控制
Chinese patent medicine
compound preparation of TCM
Ganmao Qingre granules
Schizonepetae Spi-ca
pulegone
GC
quality control
