摘要
目的通过对病理性网络使用(PIU)者执行视觉修正的Eriksen侧抑制任务的错误相关负波电位(ERN)特征检测,探讨PIU反应监控功能缺陷的发生机制。方法符合修订的《Young喇络成瘾诊断问卷》(YDQ)PIU标准的23例作为研究组,与研究组匹配性别、年龄的23例健康人作为对照组:修正的Erikson侧抑制任务包括4种靶刺激,即2种一致性刺激(〈〈〈〈〈与〉〉〉〉〉),2种不一致性刺激(〈〈〉〈〈与〉〉〈〉〉)。呈现时间250ms,被试反应时间为1100ms(包括刺激呈现时间250ms)。记录被试者执行任务时的脑电图。应用BESA5.2.0软件离线分析ERN波幅。结果PIU组错误率[(19.8±3.45)%]明显高于对照组[(13.1±2.67)%(P〈0.01);PIU组反应时间[(440±21)ms]明显短于对照组[(495±18)ins](P〈0.01)。重复测量的方差分析表明ERN波幅在组间、前额电极位点以及组间x前额电极位点显示主效应(组间:F=768,af=1,P=0.000;电极位点:F=615,af=2,P:0.000;组间×电极位点:F=516,df=2,P=0.000);组间、中央电极位点以及组间×中央电极位点显示主效应(组间:F=768,df=1,P=0.000;电极位点:F=599,df=2,P=0.000;组间x中央电极位点:F=483,df=2,P=0.000);IADERN波幅比对照组低。结论PIU存在反应监控功能功能缺陷,具有冲动控制障碍谱系的神经心理与ERP的特征,支持PIU是一种冲动控制障碍或与之相关疾病的假设。
Objective To investigate response monitoring function in individuals with pathological internet use(PIU) using the modified Eriksen flanker task by event-related potentials (ERPs). Methods 23 individuals met Young diagnostic questionnaire( YDQ ) criteria for PIU were enrolled as research group and 23 sexual-and age matched healthy persons enrolled as control group. EEG was recorded during participants performed the modi- fied Erikson flanker task. Reactive time (RT) and error rates were compared between two groups. BESA 5.2.0 was used to perform data analysis and the error-related negativity (ERN) amplitudes were analyzed. Results False alarm rate of PIU group was higher than that of control group. A repeated measure ANOVA re- vealed a significant group, frontal electrode sites and group frontal electrode sites main effect for ERN amplitudes ( for group : F = 768, df= 1, P = 0. 000 ; for frontal electrode sites : F = 615, df= 2, P = 0. 000 ; for group x frontal electrode sites : F = 516, dr= 2, P = 0. 000) , and a significant group, central electrode sites and group central electrode sites main effect for ERN amplitudes ( for group : F-- 768, dr= 1, P = 0. 000 ; for central electrode sites : F = 599, df= 2, P = 0. 000 ; for group x central electrode sites : F = 483, df= 2, P = 0.000). ERN amplitudes of PIU group were lower than those at control group. Conclusion Individuals with PIU present response monitoring dysfunctions and share neuropsychological and ERPs characteristics of compulsive-impulsive spectrum disorder, which supports that PIU is an impulse disorder or at least related to impulse control disorder.
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2012年第7期584-586,共3页
Chinese Journal of Behavioral Medicine and Brain Science
基金
江苏省自然基金项目面上课题(BK2007024)