数字减影脑血管造影阴性蛛网膜下腔出血患者认知功能的临床特点

The clinical characteristics of cognitive impairments in subarachnoid hemorrhage patients with negative digital subtraction angiography

目的通过对原发数字减影脑血管造影（DSA）阴性蛛网膜下腔出血患者认知功能的评估，分析认知功能损害的相关因素及临床特点。方法选择DSA阴性蛛网膜下腔出血患者96例，根据病情进行Fisher，Hunt—Hess分级，以简易智能量表（mini—mentalstateexamination，MMSE）进行认知功能评估，计算其发病率，统计分析认知功能损害程度与两种分级之间的相关关系。结果96例DSA阴性蛛网膜下腔出血患者认知功能损害率51．04％；认知功能损害程度与Fisher，Hunt—Hess分级密切相关（P〈0．01）。结论DSA阴性蛛网膜下腔出血患者存在不同程度的认知功能损害，Fisher，Hunt．Hess分级越高认知功能损害越严萤。

Objective To estimate the cognitive function of subarachnoid hemorrhage patients with nega- tive digital subtraction angiography （DSA）, and analyse its relevant factors and clinical characteristics. Methods 96 subarachnoid hemorrhage patients were selected, and the disease condition were classfied inte dif- ferent grades by Fisher scale, Hunt-Hess scale and the cognitive function were estimated by mini-mental state ex- amination （MMSE）, then calculated its incidence, analysed the relationship between the classification and cognitive impairments. Results The incidences of cognitive impairment in subarachnoid hemorrhage patients with negative DSA were 51.04%. Cognitive impairment was closely related to Hunt-Hess and Fisher grade （P〈0.01）. Conclusion Subarachnoid hemorrhage patients with negative DSA exist different extent of cognitive impairment. The higher Hunt-Hess or Fisher grade,the more serious cognitive impairment.