绵阳市男男性行为人群HIV感染及影响因素研究

HIV infection and influencing factors in MSM(men having sex with men) population in Mianyang,China

目的了解四川省绵阳市男男性行为人群(MSM)艾滋病病毒(HIV)感染现状及影响因素。方法以2009年用应答推动抽样法(RDS)招募的MSM队列研究纳入人员为基础进行随访调查,对随访不足基线调查样本部分,采用滚雪球采样法,依据队列纳入条件,招募补足调查对象,进行相关行为学调查和HIV等血清学检测。结果共调查检测400人,HIV初筛阳性36例,确认阳性33例,本次确认28例中新发感染9例,HIV确认感染率8.25%(33/400),本次确认感染率7.00%(28/400),新发感染率5.2/100人年。多因素分析结果显示HIV感染的独立影响因素有:年龄(OR=0.069～0.039)、职业(OR=5.200)、近1年接受同伴教育(OR=4.286)、近6月主要是偶然性伴(OR=3.650)、寻找性伴场所(OR=0.679～0.179)、累计男性性伴数(OR=9.432～34.392)、生存质量总得分(OR=608.293)、梅毒感染(OR=10.103),年龄≤25岁、工人/餐饮/商业/农民、近1年未接受过同伴教育、近6月主要是偶然性伴、酒吧/浴室寻找性伴、累计男性性伴数3～5人、生存质量得分≥80、梅毒感染者HIV感染率较高。结论绵阳市MSM人群HIV感染率较高,与人口学、性行为特征和梅毒感染及生存质量等相关,应有针对性地加大防治力度。

Objective To understand the human immunodeficiency virus（HIV） infection status and influencing factors in the population of men having sex with men（MSM） in Mianyang city,China.Methods A follow-up survey of response driven sampling（RDS） was conducted for MSM subjects recruited in a cohort study in 2009.New subjects were recruited by snowball sampling method.Uniform epidemiologic questionnaire was designed for all subjects and blood samples were collected for HIV serological detection.Results A total of 400 subjects were recruited and screened.Twenty-eight（28/400,7.00%） were confirmed HIV positive with 9 of them as new infections（5.2 new infections/100 person-year）.Multivariate analysis demonstrated the following independent factors for HIV infection：age（OR=0.069-0.039）,occupation（OR=5.200）,acceptance of peer education during last year（OR=4.286）,occasional sexual partner during last 6 months（OR=3.650）,active searching sexual partners（OR=0.679-0.179）,the cumulated number of male sexual partners（OR=9.432-34.392）,life quality score（OR=608.293）,and syphilis infection（OR=10.103）.Subjects of 25 years and younger,MSM subjects without peer education in the last 1 year,occasional sexual partner during last 6 months,bar/bathroom sex partners,accumulated 3 to 5 partners,the life quality scores equal to greater than 80,with syphilis infections showed higher HIV infection rate.Conclusions MSM population in Mianyang cityshowed higher HIV infection rate which is correlated with some demographic factors,sexual behaviors,syphilis infection status and the life quality.