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中药结合氟伐他汀治疗糖尿病肾病伴高脂血症的临床观察 被引量:4

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摘要 目的:探讨应用中药结合氟伐他汀治疗糖尿病肾病伴高脂血症的临床疗效。方法:对136例糖尿病肾病伴高脂血症的患者,给予口服中药及氟伐他汀20mg/d,检测服药前及服药后4周、8周血脂、肝功能、肾功能及载脂蛋白水平。结果:与治疗前比较,治疗后血清TC、TG、LDL-C、Lp(a)、ApoB100水平均明显降低(P<0.05);HDL-C轻微上升(P>0.05);ALT、AST、SCr无明显变化。结论:口服中药和氟伐他汀用于以低密度脂蛋白增高为特征的高脂血症的糖尿病肾病患者疗效显著。
作者 武运锁 王菲
出处 《中国医学创新》 CAS 2012年第20期133-134,共2页 Medical Innovation of China
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参考文献3

  • 1Ensah-Brown E,Parekh K.Functional capacity of macrophages det erminestheinductionoftype1diabetesa[J].Ann N Y Aead Sci,2006,1084(1):49-57.
  • 2母海艳,冯凭.C反应蛋白与糖尿病血管内皮功能[J].国际内分泌代谢杂志,2007,27(1):28-30. 被引量:16
  • 3Khalid A,Iola R,Daniel S,et a1.Efects of stylusbeyond lipid lowering:potentialfor clinicalbenefits[J].Int J Cardiol,2006,109(1):7-l5.

二级参考文献16

  • 1Lopez Rodriquze M,Gomez Cerezo J,Brobado Hemandez FJ.Endothelial dysfunction and vasculitis:a close relationship.Rev Clin Esp,2006,206:199-201.
  • 2Hu FB,Meigs JB,Li TY,et al.Inflammatory markers and risk of developing type 2 diabetes in women.Diabetes,2004,53:693-700.
  • 3Brull DJ,Serrano N,Zito F,et al.Human CRP gene polymorphism influences CRP levels.Arterioscler Thromb Vasc Biol,2003,23:2063-2069.
  • 4Khreiss T,József L,Potempa LA,et al.Conformationsl rearrangement in C-reactive protein is required for proinflammatory actions on human endothelial cells.Circulation,2004,109:2016-2022.
  • 5Schwedler-SB,Amann K,Wernicke K,et al.Native C-reactive protein increases whereas modified C-reactive protein reduces atherosclerosis in apolipoprotein E-knockout mice.Circulation,2005,112:1016-1023.
  • 6Ji SR,Wu Y,Potempa LA,et al.Effect of modified C-reactive protein on complement activation:A possible complement regulatory role of modified or monomeric C-reactive protein in atherosclerotic lesions.Arterioscler Thromb Vasc Biol,2006,26:935-941.
  • 7Nesto R.C-reactive protein,its role in inflammation,type 2 diabetes and cardiovascular disease,and the effects of insulin-sensitizing treatment with thiazolidinediones.Diabet Med,2004,21:810-817.
  • 8Ghanim H,Aljada A,Hofmeyer D,et al.Circulating monouclear cells in the obese are in a proinflammatory state.Circulation,2004,110:1564-1571.
  • 9Wang HR,Li JJ,Huang CX,et al.Fluvastatin inhibits the expression of tumor necrosis factor-alpha and activation of nuclear factor-kappaB in human endothelial cells stimulated by C-reactive protein.Clin Chim Acta,2005,353:53-60.
  • 10Verma S,Li SH,Wang CH.Hyperglycemia potentiates the proatherogenic effects of C-reactive protein:reversal with rosiglitazone.J Mol Cell Cardiol,2003,35:417-419.

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