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异柠檬酸脱氢酶基因突变及其与胶质瘤关系的研究进展 被引量：1

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摘要 胶质瘤是人中枢神经系统中最常见的肿瘤，是多因素、多阶段、多步骤参与的复杂过程，是多种基因改变累积的结果。胶质瘤生长部位特殊、多数呈浸润性生长，手术不易全切除，目前采用的手术切除辅以放化疗的综合治疗方法疗效仍不理想，预后普遍较差。
作者 金树梅 王新允
机构地区 天津市环湖医院 天津医科大学
出处 《山东医药》 CAS 2012年第27期99-101,共3页 Shandong Medical Journal
关键词 异柠檬酸脱氢酶 基因突变 胶质瘤
分类号 R739.41 [医药卫生—肿瘤]
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参考文献24

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同被引文献16

  • 1Parsons D W, Jones S, Zhang X, et al. An integrated ge- nomic analysis of human glioblastoma multiforme [ J ]. Sci- ence, 2008,321 (5897) : 1807-1812.
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山东医药
2012年 第27期

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