利用数据库对甘草属植物化学成分的分类和分布分析

Classification and distribution analysis of components in Glycyrrhiza using licorice compounds database

为系统深入地研究甘草的化学成分,本文在对甘草属植物化学成分进行全面总结的基础上,建立了甘草化合物数据库,并利用该库对化学成分重新分类,对各类化合物的分布和药用甘草的化学成分进行统计。结果显示至今甘草属植物共报道化合物422个,按结构可以分为黄酮类、香豆素类、三萜皂苷和苷元类、二苯乙烯类等4大类,以及少量其他类型化合物。目前从乌拉尔甘草中分离得到的化合物共170个,光果甘草中共134个,胀果甘草中共52个,云南甘草中共31个。本文首次增加了"二苯乙烯类"的分类类别,并将"二苄甲烷型"归为查尔酮。同时建立的数据库方便了今后对甘草的研究。

In order to study the chemical components of licorice deeply and systematically,a licorice compounds database was established after the comprehensive summary of the compounds in Glycyrrhiza.The database was used to classify the licorice components anew in order to statistically analyze the distribution of each type of compounds and the compounds in the medical Glycyrrhiza plants.The results indicated that 422 compounds had been reported in Glycyrrhiza so far,and they could be categorized into 5 classes as flavoids,coumarins,triterpenoids,stilbenoids,and some others.Up to now,170 compounds were isolated from G.uralensis,134 compounds from G.glabra,52 compunds from G.inflata,and 31 from G.yunnanensis.It is the first time to add categorization ＂stilbenoids＂,and ＂dibenzoylmethanes＂ classified as chalcones.In the meantime,the database is supposed to be convenient for further study.