摘要
目的 比较国产与进口氟康唑注射剂治疗深部真菌病临床疗效与安全性。方法 在 170例深部真菌病患者中作了前瞻性多中心研究。结果 试验组 (T组 )与对照组 (C组 )临床综合疗效痊愈率 (5 0 .9%和 5 0 .9% )、有效率 (83.6 %和89.1% )、致病菌株清除率 (83.9%和 89.1% )和不良反应发生率 (8.9%和 9.1% )之间差异均无显著性 (P>0 .0 5 )。结论 国产与进口氟康唑注射液都是安全、有效的抗真菌药物。
Objective To compare the clinical efficacy and safety of domestic and imported fluconazole injections in treating patients with deep fungal infections. [WT5,5”HZ]Methods A prospective multicentre study in 170 cases of deep fungal infections was performed. [WT5,5”HZ]Results There were no statistically significant differences in recovery rates (50.9% v 50.9%), effective rates (83.6% v 89.1%), clearance rates of fungals (83.9% v 89.1%), and side effect rates (8.9% v 9.1%) between test group and control group. Conclusion Both domestic and imported fluconazole injections are safe and effective drugs for treating deep fungal infections.
出处
《南京医科大学学报(自然科学版)》
CAS
CSCD
2000年第1期31-34,共4页
Journal of Nanjing Medical University(Natural Sciences)