非同步发育的双侧输卵管妊娠2例报告及文献回顾

Non-simultaneous Bilateral Tubal Ectopic Pregnancy:Two Case Reports and Literature Review

目的:探讨经辅助生殖技术助孕导致的非同步发育的异位妊娠的早期诊断和治疗方法。方法:回顾2例助孕治疗导致的非同步发育的双侧输卵管妊娠情况,结合文献进行分析。结果:在确定单侧输卵管妊娠的情况下,迟发的对侧输卵管妊娠易被忽略,往往需要进行二次手术来进行治疗。结论:对因为输卵管因素不孕需要进行辅助生殖技术助孕的患者,切除双侧输卵管是有效地排除非同步发育的双侧输卵管妊娠的办法。但是对于需要保留对侧输卵管的患者来说,术中对对侧输卵管的仔细检查以及术后连续随访β绒毛膜促性腺激素水平能有效发现潜在的非同步发育的异位妊娠。

Objectives：To discuss the early diagnosis of non-simultaneous ectopic pregnancy and current treatment methods. Methods：Two cases with non-simultaneous bilateral tubal ectopie pregnancy in our reproductive medical center and three cases previously reported have been reviewed. Results：The contralateral delayed ectopic pregnancy might be easily ingnored while unilateral pregnancy has been confirmed, which often needs secondary surgery. Conclusions：For the infertile women in ART with tubal factors,removal of both follopian tubes might be a solution to exclude the potential non-simultaneous bilateral tubal ectopic pregnancy while unilateral salpingectomy is performed. Otherwise,carefully examination of contralateral tube in surgery and strictly follow up of serum β-HCG after surgery facilitate to discover the potential non-simultaneous pregnancy for those people want to save another tube.