摘要近年来随着消化内镜的普及,胆汁反流性胃炎(bile reflux gastritis,BRG)的检出率逐渐增加,并日益受到重视。本研究通过检测BRG患者胃液中和胃黏膜组织内的总胆汁酸(total bile acids,TBA)浓度,分析其相关性,并参照相对应的胃镜及病理表现,评价胆汁反流对胃黏膜炎性反应的影响程度。
2Kellosalo J, Alavaikko M, Laitinen S. Effect of biliary tract procedures on duodenogastric reflux and the gastric mucosa. Seand J Gastroenterol, 1991, 26 1272-1278.
3Milner JD, Orekov T, Ward JM, et al. Sustained IL-4 exposure leads to a novel pathway for hemophagoeytosis, inflammation, and tissue macrophage accumulation. Blood, 2010,116 : 2476-2483.
4Cui X, Yang SC, Sharma S,et al. IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer. Biochem Biophys Res Commun, 2006,343:995-1001.
5Seicean A, Popa D, Mocan T, et al. Thl and Th2 profiles inpatients with pancreatic cancer compared with chronic pancreatitis. Pancreas, 2009, 38..594-595.