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1，25羟基维生素D3通过其核受体与膜受体协同调节骨代谢机制的研究进展 被引量：6

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摘要 1，25羟基维生素D3[1，25-ihydroxyvitamin D3，1，25（OH）2D31是维持机体钙磷离子代谢平衡的主要调节者之一，1，25（OH）2D，缺乏可导致钙质吸收和骨矿化障碍，引起佝偻病的发生：机体钙磷代谢失调可以导致诸如骨质疏松症、骨质软化症等疾病的发生。
作者 赵成毅 刘少喻 李青 袁元杏 梁道臣 张爱明
机构地区 中山大学附属第一医院 中山市人民医院
出处 《中华骨科杂志》 CAS CSCD 北大核心 2012年第8期788-791,共4页 Chinese Journal of Orthopaedics
关键词 25羟基维生素D3 协同调节 骨矿化 代谢机制 膜受体 核受体 钙磷离子 骨质疏松症
分类号 R580 [医药卫生—内分泌]
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参考文献32

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同被引文献76

  • 1张艳梅.羟基-D_3的生理功能和机理研究[J].山西农业科学,2006,34(2):76-78. 被引量：8
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  • 3Holick M F, Chen T C. Vitamin D deficiency: a worldwide problem with health consequences[J]. Am J Clin Nutr, 2008, 87(4) : 1080S - 1086S.
  • 4Visser M, Deeg D J, Puts M T, et al. Low serum concentrations of 25- hydroxyvitamin D in older persons and the risk of nursing home admis- sion[J]. Am J Clin Nutr, 2006, 84(3) : 616 -622.
  • 5Meguid N A, Hashish A F, Anwar M, et al. Reduced serum levels of 25-hydroxy and 1,25-dihydroxy vitamin D in Egyptian children with autism[J]. J Altem Complemer Med, 2010, 16(6) : 641 -645.
  • 6Zittermann A. Vitamin D and disease prevention with special reference to cardiovascular disease[ J]. Prog Biophys Mol Biol, 2006, 92 ( 1 ) : 39 - 48.
  • 7Forman J P, Giovannueei E, Holmes M D, et al. Plasma 25- hydroxyvitamin D levels and risk of incident hypertension [ J]. Hyper- tension, 2007, 49 (5) : 1063 - 1069.
  • 8Bischoff-Ferrari H A, Dietrich T, Orav E J, et al. Higher 25- hydroxyvitamin D concentrations are associated with better lower-ex- tremity function in both active and inactive persons aged > or = 60 y [J]. Am J Clin Nutr, 2004, 80(3) : 752 -758.
  • 9Chapuy M C, Arlot M E, Duboeuf F, et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women[ J]. N Engl J Med, 1992, 327(23) : 1637 - 1642.
  • 10Garland C, Gorham E D, Mohr S B, et al. Vitamin D for cancer pre- vention: global perspective[J]. Ann Epidemiol, 2009, 19(7) : 468 - 483.

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中华骨科杂志
2012年 第8期

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