摘要
目的观察颈脉康配方颗粒治疗糖尿病颈动脉粥样硬化斑块的临床疗效。方法将210例糖尿病颈动脉粥样硬化斑块患者随机分为3组,每组70例,C组仅常规西医治疗,A组在C组基础上给予颈脉康配方颗粒口服,B组在C组基础上给予辛伐他汀滴丸口服,疗程均为3个月。结果 A组总有效率均优于B、C组(P<0.05)。A组治疗后空腹血糖(FBG)、糖化血红蛋白(HbA1c)与B组比较,差异有统计学意义(P<0.05);A组治疗后FBG、HbA1c、三酰甘油、总胆固醇与C组比较,差异有统计学意义(P<0.05)。A组治疗后全血黏度低切、红细胞聚集指数优于B组(P<0.05)。彩色多普勒超声示A组治疗后降低颈动脉内膜-中层厚度(IMT)、Crouse斑块积分与C组比较,差异有统计学意义(P<0.05)。结论颈脉康配方颗粒治疗糖尿病颈动脉粥样硬化斑块疗效显著。
Objective To observe the clinical effect of Jingmaikang granula on diabetes carotid artherosclerosis plaques.Methods Two hundred and ten patients with diabetes carotid artherosclerosis plaques were randomly divided into three groups,70 patients for each group.Group C was given common medication,group A was given Jingmaikang granula and group B was given Simvastatin additionally.The course of treatment was 3 months.Results The total effective rate of group A was superior to group B and group C respectively(P〈0.05).After treatment,there was significant difference in FBG and HbA1c between group A and group B(P〈0.05).The level of FBG,HbA1c,TG and TC significantly decreased in group A compared with group C(P〈0.05).The level of blood viscosity,red blood cell aggregation index in group A significantly decreased compared with group B(P〈0.05).Color Doppler imaging showed that the level of IMT and Crouse plaques integral in group A significantly decreased compared with group C(P〈0.05).Conclusion Jingmaikang granula is effective in the treatment of diabetes carotid artherosclerosis plaques.
出处
《中国中医药信息杂志》
CAS
CSCD
2012年第7期10-12,共3页
Chinese Journal of Information on Traditional Chinese Medicine
基金
泰安市科技计划项目(20103015)
关键词
糖尿病
颈动脉粥样硬化斑块
颈脉康配方颗粒
diabetes mellitus; carotid artherosclerosis plaques; Jingmaikang granula