儿童肥胖与性早熟的研究进展

Research progress of childhood obesity and precocious puberty

自20世纪60年代起,儿童性早熟的发病率与儿童肥胖率呈连年上升趋势。专家指出儿童肥胖与性早熟确实存在关联。研究发现肥胖女童的性早熟发病率显著高于正常体质量女童;但在男童方面,情况较为复杂。瘦素被认为是儿童肥胖与性早熟的纽带因素,其与肥胖儿童性早熟关系的相关研究也有较多报道。该文就儿童肥胖与性早熟的研究进展作一综述。

Since 1960s, the prevalences of precocious puberty and childhood obesity have been rising, and it has been pointed out by many experts that childhood obesity may be relevant with precocious puberty. Some studies have revealed that the prevalence of precocious puberty in obese girls is significantly higher than that in girls with normal body weight. However, the results are complicated when it comes to boys. Leptin may be one of the links between childhood obesity and precocious puberty, and there have been many reports about its relationship with precocious puberty in children with obesity. The research progress of childhood obesity and precocious puberty is reviewed in this paper.