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骨髓间充质干细胞与终末期肝病 被引量：2

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摘要 由于乙型肝炎病毒（hepatitis B virus,HBV）感染率较高,感染者进而罹患急慢性肝炎、肝纤维化乃至肝硬化、肝癌的事件屡见不鲜,肝脏疾病目前已经成为中国医疗卫生的主要负担之一[1]。肝脏疾病进展到肝硬化等终末期肝病时,通常累及广泛肝实质细胞,肝组织再生能力下降,造成肝功能失代偿并最终导致肝功能衰竭[2]。常规的内科保肝治疗效果不佳,病死率很高。目前原位肝移植仍然是治疗终末期肝病最有效的措施,
作者 胡祥 刘沐芸 杨晓菲
机构地区 深圳市北科细胞工程研究所
出处 《中华细胞与干细胞杂志（电子版）》 2012年第1期52-56,共5页 Chinese Journal of Cell and Stem Cell（Electronic Edition）
关键词 终末期肝病 骨髓间充质干细胞 乙型肝炎病毒 肝功能失代偿 肝脏疾病 治疗效果 急慢性肝炎 肝实质细胞
分类号 R657.3 [医药卫生—外科学]
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共引文献81

同被引文献14

  • 1吴理茂,李连达,刘红,宁可永,李贻奎.自体骨髓干细胞移植与归元方联用治疗急慢性肝损伤实验研究[J].中国工程科学,2004,6(7):34-42. 被引量：27
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  • 8孙文静,王军,胡辂,兰春慧,陈东风.干细胞向肝细胞诱导分化机制的研究进展[J].医学综述,2010,16(9):1311-1313. 被引量：2
  • 9赵磊,曲强,卫金花,何小东.骨髓间充质干细胞移植治疗终末期肝病:现状与前景[J].生命科学,2010,22(4):367-371. 被引量：2
  • 10邢秀伟,李建生.干细胞移植治疗肝脏疾病的研究进展[J].中国组织工程研究,2012,16(6):1115-1118. 被引量：7

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中华细胞与干细胞杂志（电子版）
2012年 第1期

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