剖宫产患者围术期抗菌药物应用状况分析

The Application Analysis of Antibacterial Agents in Patients Undergoing Cesarean Section

目的探讨我院剖宫产患者围术期抗菌药物的应用情况,为临床合理用药提供参考。方法采用回顾性分析方法对2008年8月—2011年8月在我院产科行剖宫产手术患者的临床资料进行分析。结果⑴抗菌药物的使用情况:587例剖宫产患者术中均使用抗菌药物,位于前3位的为头孢呋辛钠(48.55%)、青霉素G(16.35%)和甲硝唑(12.93%);抗菌药物平均用药疗程均超过7d。⑵抗菌药物使用时间:所有患者均在术前30～60min静脉滴注抗菌药物,术后使用抗菌药物时间集中在3～6d。⑶抗菌药物合理应用评价:我院抗菌药物应用基本合理,但仍存在不合理之处。结论我院剖宫产手术患者围术期抗菌药物应用存在不足之处,主要表现为用药开始时间、用药持续时间、剂量、给药方法及联合应用不合理,临床医生应加强关注。

OBJECTIVE To explore the application of antibacterial agents in patients undergoing cesarean section in order to its rational drug use. METHODS From August 2008 to August 2011, the clinical dates of cesarean section patients were reviewed retrospectively. RESULTS （1）The use condition： 587 patients of cesarean section were used antibacterial agents in operation, the first 3 place of antibacterial agents were cefuroxime sodium（48.55%）, penicillin（16.35%） and metronidazole （12.93%）. Average drug treatment was 7 days. （2）The service time of antibacterial agents ： all patients were given antibacterial agents before operation（30~60 min）, the service time of antibacterial agents was 3~6 days after operation.（3）The evaluation of rational use of antibacterial agents： the application of antibacterial agents was rational, but exists some irrationality. CONCLUSION The application of antibacterial agents has disadvantage, the manifestation are not reasonable of drug start time, drug duration, dosage, administration and joint application. Clinical doctors should pay attention to the unreasonable application.