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尿酸水平与高血压关系的临床研究 被引量：3

The relationship between the level of uric acid and hypertension
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摘要 目的探讨尿酸水平与高血压的关系。方法对德州市城镇职工98 488人查体资料进行横断分析。结果高尿酸血症组男性和女性高血压患病率与非高尿酸血症组相比,差异均有统计学意义(P<0.05)。结论高尿酸血症是导致高血压的危险因素,高尿酸血症对女性患者罹患高血压的风险(OR=3.979)是男性(OR=2.064)的1.93倍。 Objective To study the relationship between the level of uric acid and hypertension.Methods To analyse the data of health examination from workers in Dezhou city by cross-sectional research.Results The hypertensive prevalences of both males and females in hyperuricemia group were both significantly higher than that of those in non-hyperuricemia group.Conclusion Hyperuricemia is a risk factor leading to hypertension.The risk of hypertension in female patients with hyperuricemia（OR=3.979） are 1.93 folds higher than that in male patients with hyperuricemia（OR=2.064）.
作者 董茂江 吴继卫
机构地区 德州学院医学系
出处 《重庆医学》 CAS CSCD 北大核心 2012年第20期2023-2024,共2页 Chongqing medicine
基金 山东省医药卫生科技发展项目(2009HZ005)
关键词 高尿酸血症 高血压 危险因素 hyperuricemia hypertension risk factors
分类号 R589.7 [医药卫生—内分泌] R544.1 [医药卫生—心血管疾病]
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参考文献7

  • 1张立晶,胡大一,杨进刚,许玉韵,李田昌,王国宏,史旭波,路亚枫.有心血管疾病危险因素人群中高尿酸血症的发生率及其相关因素[J].首都医科大学学报,2005,26(2):124-127. 被引量：56
  • 2Sundstrom J, Sullivan LD, Agostino RB, et al. Relation of serum uric acid to longitudinal blood pressure tracking and hypertension incidence [J]. Hypertension, 2005, 45 (1) :28-33.
  • 3中国医师协会心血管内科医师分会.中国医师协会循证医学专业委员会,无症状高尿酸血症合并心血管疾病诊治建议中国专家共识[J].中国全科医学,2010,:13-1149,1145.
  • 4刘力生,王文,姚崇华.中国高血压防治指南(2009年基层版)[J].中华高血压杂志,2010,18(1):11-30. 被引量：861
  • 5MazaliM,Hughes J,Kim YG,et al. Elevated uric acid in creases blood pressure in lhe rat by a novel crystalinde- pendent mechanism[J].Hypertension, 2001,38 ( 5 ) : 1101- 1106.
  • 6EI Atat FA, Stas SN, Mcfarlane SI, et al. The relationship between hyperinsulinemia, hypertension and progressive renaldisease [J].SoeNephro, 2004,15 ( 11 ) : 2816-2827.
  • 7颜秉菊,蔡久英.高尿酸血症与冠心病及其危险因素的研究进展[J].医学综述,2006,12(14):854-856. 被引量：24

二级参考文献27

共引文献939

同被引文献23

  • 1余俊文,陆锦波,张小娟,杨延斌,余寿益,刘奔流.1320名老年人血尿酸与血脂、血糖和血压的分析[J].中华流行病学杂志,2005,26(6):455-457. 被引量：98
  • 2中国高血压防治指南修订委员会.中国高血压防治指南(2010年修订版)[M].北京:人民卫生出版社,2011:1.
  • 3LohsoonthornV, DhanamunB, WilliamsMA. Prevalence of hyperuricemia and its relationship with metabolic syndrome in Thai adults receiving annual health exams[J]. Arch Med Res, 2006,37(7):883-889. DOI: 10.1016/j.arcmed.2006.03.008.
  • 4K?ttgenA, AlbrechtE, TeumerA, et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations[J]. Nat Genet, 2013,45(2):145-154. DOI: 10.1038/ng.2500.
  • 5KolzM, JohnsonT, SannaS, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations[J]. PLoS Genet, 2009,5(6):e1000504. DOI: 10.1371/journal.pgen.1000504.
  • 6StarkK, ReinhardW, GrasslM, et al. Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease[J]. PLoS One, 2009,4(11):e7729. DOI: 10.1371/journal.pone.0007729.
  • 7WangB, MiaoZ, LiuS, et al. Genetic analysis of ABCG2 gene C421A polymorphism with gout disease in Chinese Han male population[J]. Hum Genet, 2010,127(2):245-246. DOI: 10.1007/s00439-009-0760-4.
  • 8MooreJH. The ubiquitous nature of epistasis in determining susceptibility to common human diseases[J]. Hum Hered, 2003,56(1-3):73-82.
  • 9WallaceSL, RobinsonH, MasiAT, et al. Preliminary criteria for the classification of the acute arthritis of primary gout[J]. Arthritis Rheum, 1977,20(3):895-900.DOI:10.1002/art.1780200320.
  • 10JungDH, LeeYJ, LeeHR, et al. Association of renal manifestations with serum uric acid in Korean adults with normal uric acid levels[J]. J Korean Med Sci, 2010,25(12):1766-1770. DOI: 10.3346/jkms.2012.25.12.12.1766.

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重庆医学
2012年 第20期

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