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阿尔茨海默病突触功能障碍与Aβ的关系 被引量:1

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摘要 阿尔茨海默病(AD)是不可逆、进行性脑病,缓慢损害记忆和认知功能,是最常见的痴呆类型,给患者、家属和社会带来沉重的经济和精神负担。年龄是最重要的危险因素。65岁以后每隔五年AD发病率翻番。AD也可在中年发病,早发型痴呆指65岁之前发病的痴呆类型,较少见,其病理表现与晚发型相似。临床上AD的确切发病时间难以确定,常常表现为轻微发作性记忆障碍,之后出现数月的缓慢进展,并出现其他认知功能损害,数年后出现显著的痴呆。
出处 《中国煤炭工业医学杂志》 2012年第7期1129-1131,共3页 Chinese Journal of Coal Industry Medicine
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