艾蒿油乳液稳定性的油相离心系数法表征

Characterization of the stability of artemisia oil emulsion with oil-phase centrifugal coefficient method

以N-十二烷基亚氨基二丙酸二钠(NCNA)和失水山梨醇单油酸酯(Span80)为乳化剂,采用界面复合物生成法制备艾蒿油乳液,通过油相离心系数对艾蒿油乳液的稳定性进行表征.讨论了搅拌速度、乳化温度、乳化时间、乳化剂质量分数、乳化剂配比等因素对乳液稳定性的影响.结果表明:搅拌速度为3 000 r/min、温度为60℃、乳化时间为15 min、乳化剂质量分数为5%、m(Span80)/m(NCNA)=8/2时油相离心系数为0,乳液最稳定.通过多媒体显微镜和透射电镜观察了乳液液滴的分布及大小形态,在最佳条件下制备的乳液液滴粒径集中分布在20～50 nm.

The artemisia oil emulsion was prepared by the interfacial complexes generation method using disodium N-（2-carboxyethyl）-N-dodecyl-β-alaninate （NCNA） and dehydrated sorbitol monooleate （Span80） as emulsifiers. The stability of the emulsion was characterized by the oil-phase centrifugal coefficient method. The effects of stirring speed, emulsification temperature, emulsification time, emulsifier dosage and emulsifier ratio on the stability of emulsion were investigated. The results showed that the optimum emulsification condi- tions were： stirring speed 3 000 r/min, emulsification temperature 60 ℃, emulsification l：ime 15 min, emulsifier dosage 5%, emulsifier ratio （Span80/NCNA） 8/2. In this condition the oil-phase centrif Jgal coefficient was 0, and the emulsion was the most stable. Meanwhile, multimedia microscope and transmission electron micro- scope （TEM） were used to observe the distribution and morphology of the emulsion droplet, and the concen- trated distribution was in the range of 20-50 nm under the optimum emulsification conditions.