2008-2010年我院药品不良反应情况分析

Analysis on ADR Case Reports in Our Hospital during 2008-2010

目的:了解我院2008～2010年药品不良反应(ADR)的发生和分布情况,为临床用药提供参考。方法:将我院2008～2010年临床科室上报的558份《药品不良反应/事件报告表》,按患者的性别、年龄、药品种类、不良反应主要临床表现等进行分类统计和分析。结果:抗感染药物的ADRs报告例数位居第1位,为308例,占55.20%,其中以头孢菌素类引起的ADRs最高(122/308,39.61%);皮肤及其附件ADR发生频率最高,为198例,占31.88%。结论:应提高临床医护人员的安全用药意识,从而减少、避免ADR的发生,保障公众用药安全。

Objective： To realize the adverse drug reactions （ADR） in our hospital, and to provide reference for safe clinical usage. Methods： The age and sex of patients, the kind of drugs and clinical manifestations were analysed on 558 ADR cases. Results： 308 cases were induced by anti - Infective drugs （55. 20% ）, among them with the highest ADRs caused by cephalo- sporin （ 122/308, 39. 61% ） ; 198cases showed cutaneous injury 31. 88% ）. Conclusions： we should improve the consciousness of safe medication use, so as to reduce and avoid ADR, protect public safety of herbal medicines.