颈动脉粥样硬化与脑梗死的临床研究

A clinical study of carotid atherosclerosis and cerebral infarction

目的探讨颈动脉粥样硬化与脑梗死的相关性。方法对137例脑梗死患者的颈动咏彩色多普勒超声检查和血压、血糖、血脂等相关资料进行回顾性分析。结果脑梗死患者颈动脉粥样硬化斑块的发生率较高（69．34％），在颈动脉分叉处最为多见（77．9％），以软斑为主（41．1％），且颈动脉硬化斑块发生与梗死有同侧相关性。颈动脉粥样斑块与性别、高血压、高血糖、高血脂有明显的相关性（P〈0．05）。结论颈动脉粥样硬化与脑梗死的关系密切，而男性、高血压、糖尿病、高脂血症又加速颈动脉粥样硬化的发生及斑块的形成。

Objective To explore the correlation of carotid atherosclerosis with cerebral infarction. Methods Using a retrospective analysis, we reviewed the data on 137 patients with cerebral infarction, including the findings of Carotid Colored Doppler ultrasonography, blood pressure, and blood glucose and lipids. Results The incidence of atherosclerotic plaque was higher in the patients with cerebral infarction （ 69.34% ）. Atherosclerotic plaque mostly devel- oped in the crotch of carotid artery （ 77.9% ）, mostly being soft plaque （ 41.1% ）. The formation of atherosclerotic plaque was laterally related with infarction. Gender, hypertension, and elevated levels of blood glucoseand and lipids were markedly related with carotid atherosclerotic plaque （ P 〈 0.05 ）. Conclusions Carotid atherosclerosis s closely related with cerebral infarction. Male, hypertension, diabetes, and hyperlipoidemia can accelerate the occurrence of carotid atherosclerosis and the formation of plaque.