连续性血液净化治疗老年危重症合并低血压的疗效观察

Application and Clinical Intervention of CBP in Treating Aged Cases with Intensive Diseases and Hypotension

目的观察连续性血液净化治疗老年危重症合并低血压的疗效。方法将2009年4月—2011年10月收治的87例老年危重症患者分为观察组与对照组,对照组采用常规治疗等,观察组选用连续性静脉-静脉血液滤过模式治疗,观察两组疗效。结果观察组治疗后24、48、72h与治疗前及对照组治疗后APACHE-Ⅱ评分差异有统计学意义(P<0.05),观察组治疗前后心率、血肌酐、乳酸、pH及平均动脉压差异有统计学意义(P<0.05),观察组治疗后心率、血肌酐、乳酸、pH较对照组差异有统计学意义(P<0.05),平均动脉压差异无统计学意义(P>0.05)。结论连续性血液净化对于老年危重症并低血压患者较常规透析治疗效果、安全性更高。

Objective The application experience, clinical effect and clinical intervention measure of CBP in treating aged patients with intensive diseases and hypotension were observed in this paper. Methods The clinical data of 87 aged cases that suffered intensive diseases and were treated in the First Affiliated Hospital of Guangdong Pharmaceutical University was ana- lyzed retrospectively. Results It was observed that APACHE - II of observation group after treatment for 24h, 48h, and 72h was significantly different from that of before treatment and control group after treatment （P 〈0. 05 ） ; the differences of observa- tion group before and after treatment were significant in heart rate, CRE, lactic acid, pH and MBP （P 〈 O. 05） ; observation group was significantly different from control group in heart rate, CRE, lactic acid, and pH （P 〈 0. 05 ）, but MBP was insignif- icantly different （P 〉 0. 05）. Conclusion The treatment effect and security of CBP in treating aged patients with intensive dis- eases and hypotension are better and higher respectively in contrast to conventional hemodialysis.