新型多齿手性氨基醇的合成和结构表征

Synthesis and structure characterization of novel polydentate chiral amino alcohols

以L-苯甘氨酸和N,N-二甲基苯胺为原料,合成了2种新型多齿手性氨基醇S-1,1,2-三苯基-2-[(2-二甲氨基-5-溴-1-苯基)甲氨基]-1-乙醇和S-2-苯基-2-[(2-二甲氨基-5-溴-1-苯基)甲氨基]-1-乙醇;利用红外光谱仪、核磁共振谱仪及质谱仪表征了合成产物的结构.

Two novel polydentate chiral amino alcohols,S-2-[（5-bromo-2-dimethylamino-1-phenyl）methylamino]-1,1,2-triphenyl-1-ethanol and S-2-[（5-bromo-2-dimethylamino-1-phenyl）methylamino]-2-phenyl-1-ethanol,were conveniently and effectively synthesized from L-benzene glycine and N,N-dimethylaniline as the starting materials.The structure of as-synthesized products was characterized by means of infrared spectrometry,nuclear magnetic resonance spectroscopy,and mass spectrometry.