期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

胎儿病毒感染与先天性心血管畸形 被引量：3

Prenatal viral infectiotn and congenital cardiovascular malformations
原文传递
导出
摘要 先天性心血管畸形是小儿最常见的先天性心脏病，胎儿期病毒感染与其发生关系密切。先天性心脏病严重危害儿童身心健康，明确其病因对预防和治疗先天性心脏病有重要的意义。该文综述宫内病毒感染导致先天性心脏病的病因、病毒传播途径、发病机制及预防措施。 As the most common disease for children with congenital heart disease （CHD）, congenital cardiovascular malformations have been closely associated with prenatal viral infectiotn. It is important to clarify the etiology of these diseases because the levels of physical and mental health for children with CHD are seriously damaged, and it also improves the levels of preventing and treating these diseases. This review focuses on the way of infection ,pathogenesis and prevention measures for intrauterine viral infections leading to CHD.
作者 赵青松(综述) 吴德 都鹏飞(审校)
机构地区 安徽医科大学第一附属医院儿科 安徽医科大学第二附属医院儿科
出处 《国际儿科学杂志》 2012年第4期411-413,431,共4页 International Journal of Pediatrics
关键词 胎儿 病毒感染 先天性心血管畸形 Fetus Viral infectiotn Congenital cardiovascular malformation
分类号 R541.1 [医药卫生—心血管疾病]
  • 相关文献

参考文献5

二级参考文献47

  • 1Jerome LA, Papaioannou VE. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbxl. Nat Genet, 2001,27 (3) : 286-291.
  • 2Lindsay EA, Vitelli F, Su H, et al. Tbxl haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature, 2001,410 (6824) :97-101.
  • 3Yagi H, Fumtani Y, Hamada H, et al. Role of TBX1 in human de122q1 1.2 syndrome. Lancet, 2003,362 (9393) : 1366-1373.
  • 4Basson CT, Huang T, Lin RC, et al. Different TBX5 interactions in heart and limb defined by Hoh-Oram syndrome mutations. Proc Natl Acad Sci USA, 1999,96(6) :2919-2924.
  • 5Satoda M,Zhao F,Diaz GA,et al. Mutations in TFAP2βcause Char syndrome,a familial form of patent ductus arterlosus. Nat Genet,2000,25( 1 ) :42-46.
  • 6Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet, 2001,29(4) :465-468.
  • 7Chen B, Bronson RT, Klaman LD, et al. Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis. Nat Genet, 2000, 24 (3) : 296-299.
  • 8Niihori T, Aoki Y, Narumi Y, et al. Germline KRAS and BRAF mutations in Cardio-Facio-Cutaneous syndrome. Nat Genet, 2006,38(3) : 294-296.
  • 9Aoki Y, Niihori T, Kawame H, et al. Gemdine mutations in HRAS protooncogene cause Costello syndrome. Nat Genet, 2005,37(10) : 1038-1040.
  • 10Schubbert S, Zenker M, Rowe SL, et al. Gennline KRAS mutations cause Noonan syndrome. Nat Genet, 2006,38 (3) : 331-336.

共引文献42

同被引文献20

  • 1Liang Z, Wu L, Fan L, et al. Ambient air pollution and birth defects in Haikou city,Hainan province[ J]. BMC Pediatr,2014,14( 1 ) :283.
  • 2Julihn A, Jansson P, Regnstrand T, et al. Is congenital malformation a risk factor for caries development in Swedish adolescents? [ J ]. Acta Odontol Scand ,2013,71 ( 6 ) : 1636 - 1644..
  • 3Cesario B, Stefania T, Guido DS, et al. Benzodiazepine exposure in preg- nancy and risk of major malformations: a critical overview [ J ]. General Hospital Psychiatry,2013,35( 1 ) :3 - 8.
  • 4Wu J, Zhang C, Pei L, et al. Association between risk of birth defects oc- curring level and arsenic concentrations in soils of Lvliang, Shanxi pro- vince of China [ J ]. Environ Pollut ,2014,191 : 1 - 7.
  • 5Lin Y,Shu S, Tang S. A case-control study of environmental exposures for nonsyndromic cleft of the lip and/or palate in eastern Guangdong, China[ J]. Int J Pediatr Otorhinolaryngo1,2014,78 ( 3 ) :544 - 550.
  • 6Yang W,Zeng L, Cheng Y, et al. The effects of periconceptional risk fac- tor exposure and micronutrient supplementation on birth defects in Shaanxi Province in Western China [ J ]. PLoS One, 2012,7 ( 12 ) : e53429.
  • 7Liu J, Wang XF, Wang Y, et al. The incidence rate, high-risk factors, and short- and long-term adverse outcomes of fetal growth restriction: a report from China's Mainland[ J]. Medicine (Baltimore) ,2014,93 ( 27 ) : e210.
  • 8Yang M, Zhang S, Du Y. Epidemiology characteristics of birth defects in Shenzhen city during 2003 to 2009, China [ J ]. J Matem Fetal Neonatal Med ,2014,30 : 1 - 5.
  • 9Lamberty CO, de Carvalho MH, Miguelez J, et al. Ultrasound detection rate of single umbilical artery in the first trimester of pregnancy [ J ]. Prenat Diagn, 2011,31 ( 9 ) : 865 - 868.
  • 10Marshall EG, Gensburg LJ, Deres DA, et al. Maternal residential expo- sure to hazardous wastes and risk of central nervous system and muscu- loskeletal birth defects [ J ]. Arch Environ Health, 1997,52 ( 6 ) :416 - 425.

引证文献3

二级引证文献26

国际儿科学杂志
2012年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部