复方口服避孕药的非避孕用途及风险

Non-contraceptive benefits and risk of compound oral contraceptives

口服避孕药的种类繁多,其临床用途与其主要成分的药代动力学和药理作用密切相关。复方口服避孕药除了具有确切的避孕效果外,确有对某些疾病的防治作用如治疗青春期和围绝经期功能失调性子宫出血、防止骨质疏松、降低子宫内膜癌和卵巢肿瘤的风险等。但是,临床应用标准差异较大,且存在一定的用药风险。复方口服避孕药在临床非避孕应用方面存在确切的疗效,但还需要在今后的工作中加强对其效益与风险的评价,合理应用药物,充分发挥复方口服避孕药最有效的作用。

tn addition to the exact contraceptive effect, compound oral contraceptives（COC） is indeed able to prevent and treat certain diseases, such as treatment of adolescent and perimenopausal dysfunctional uterine bleeding, to prevent osteoporosis, to lower the incidence of endometrial cancer and ovarian cancer risk, etc. However, the standards of clinical application is quite different and certain risks exist. The non-contracepUve benefits of COC; is exacL In future, it also need to strengthen the benefits and risks evaluation of COC, and make application of drugs more reasonable, to play the most effective role of COC.