Bobath技术对急性脑梗死患者运动功能及TNF-α的影响

Effect of Bobatht treatment on motor function and TNF-α in patients with acute cerebral infarction

目的观察Bobath技术对急性脑梗死(ACI)患者肢体运动功能及肿瘤坏死因子α(TNF-α)含量的影响。方法将60例ACI患者随机分为2组,治疗组30例采用Bobath技术和药物加电针等常规治疗,对照组30例仅采用药物加电针等常规治疗。用电化学发光技术,测定2组治疗前和治疗第10天、第20天TNF-α水平。用简化Fugl-Meyer及Barthel指数评定患者的运动功能。结果治疗组第10天、第20天后TNF-α水平较对照组明显降低(P均<0.05);治疗组第10天、第20天后Fugl-Meyer评分、Barthel指数评分均高于对照组(P均<0.05)。结论 Bobath技术能促进ACI患者运动功能的恢复,并对细胞因子产生一定的影响。

Objective It is to observe the effect of Bobath treatment on limb motor function and tumor necrosis factor α （ TNF - α） level in patients with acute cerebral infarction （ACI）. Methods Sixty patients with ACI were randomly divided in- to a treatment group （ n = 30） and a control group （ n = 30 ）. All patients were treated with regular therapy with Ligustrazine Hydrochoride and Sodium Chloride Injection, while the treatment group received Bobath treatment. The TNF - α level was measured by electroche mole minescence before treatment and in 10,20 days after treatment; motor function was evaluated by Barthel index and Fugl - meyer. Results The TNF - α level was significantly lower in treatment group in 10,20 days after treatment than that in control group（ P 〈 0. 05 ） Fugl -meyer scores and Barthel index were higher in the treatment group than those in the control group after 10 and 20 days＇treatment（ P 〈 0.05 ）. Conclusion Bobath treatment could promote the recovery of motor function and ADL in patients with ACI, and has some influence on cytokines.