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食管癌易感性与AG01rs636832A〉G基因多态性的关系 被引量:1

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摘要 miRNA与Dicer、TAR—RNA结合蛋白、Argonaute(AGO)等蛋白形成微小RNA介导基因沉默复合体(miRNP),在转录后水平调控基因表达,参与调控细胞生长、分化和凋亡,其中以AGO蛋白最为重要。单核苷酸多态性(SNP)是基因水平上单个核苷酸的变异,是形成肿瘤易感性的原因之一。本实验旨在探讨AGOIrs636832A〉GSNP与食管癌易感性的关系。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第7期1366-1366,共1页 Chinese Journal of Experimental Surgery
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