早期股骨头缺血性坏死的治疗

Treatment of early stage avascular necrosis of the femoral head

骨坏死是一种进展性和致残性疾病,主要影响负重关节,髋关节是最常受累的关节。早期股骨头缺血性坏死主要采用药物或生物物理治疗等非手术疗法和保头手术治疗,但目前为止还没有一种治疗方法能达到理想的治疗效果。针对塌陷前期股骨头缺血性坏死的治疗,改进的股骨头髓芯减压术仍是目前最安全有效常用的方法。近来髓芯减压术联合使用不同的生长和分化因子进一步提高了治疗效果,是当前研究的热点。早期诊断是股骨头缺血性坏死治疗的关键,以髓芯减压术为基础的综合性治疗仍然是当今的主要趋势。

Avascular necrosis is a progressively devastating disease and primarily affects weight-bearing joints. The hip is the most commonly affected joint. In early stage,nonoperative （including pharmacologic intervention and biophysical treat- ments）and operative modalities for protecting hip joint have become the main therapeutic methods. However there is still no satisfied mothod with reasonable effect. According to the treatment of the avascular necrosis of the femoral head of the pre-col- lapse stage, core decompression with modification of technique is still one of the safest and most commonly employed proce- dures. Recently there have been attempts to enhance the effect of core decompression with use of various growth and differentiation factors. Which is the hot spot of current research. Early diagnosis is the key to the treatment of the avascular necrosis of the femoral head. Comprehensive treatment which is based on the core decompression is still the main treatment of today.