光纤传感技术快速检验舒必利片

Rapid detection of Sulpiride Tablets by optic fiber sensing technologies

目的建立光纤传感技术对舒必利片快速定性、定量分析的方法。方法采用光纤传感装置,将光纤探头直接插入待测样品溶液中,氘灯发出的光通过光纤传输到达探头,经探头感受溶液吸收的光信号,并再次通过光纤反馈到CCD检测器,最终通过计算机可瞬间获得待测样品的光纤紫外-可见吸收光谱,使用系统软件直接读取相关参数,实现了舒必利片的快速定性、定量分析。结果该法测定的最大吸收波长及含量均在中国药典规定的范围内,并与药典含量测定方法进行一致性比较,结果表明2种测定方法差异无统计学意义(P>0.05)。结论光纤传感技术实现了对舒必利片快速定性和定量分析。

Objective To establish a rapid and effective method to analyze contents of Sulpiride Tablets qualitatively and quantitatively. Methods By employing optic fiber sensing device,the probe was put directly into sample solution;and light ray emit by deuteri- um lamp was led to the probe through optical fiber transmission;through probe sensing and sample solution absorption, light signal was generated and was fed back to CCD detector again through optical fiber. And finally UV-Vis absorption spectrum was obtained instantaneously from sample solution through computer. Related parameters were directly read by software system so as to achieve rapid qualitative and quantitative analysis of Sulpiride Tablets. Results The maximum absorbent wavelength detected from this method and contents were proved to be within the limit proposed by Chinese Pharmacopoeia. And compared with the method pre-scribed in the pharmacopoeia,the results indicated that there was no significant difference between the two methods （P〉0.05）. Conclusion Optic fiber sensing technology achieves rapidly qualitatively and quantitatively analysis of Sulpiride Tablets.